Karachi, a city of around 20 million people, is facing a crisis of governance that is reflected in the poor state of service delivery, and unplanned and unsustainable urbanisation. The city’s development shortcomings, and attendant social, economic and environmental challenges, have created vulnerabilities at different scales that are likely to exacerbate the impacts of climate change-related weather events taking place within the city and elsewhere in the country. This report is a step towards identifying and highlighting some of these vulnerabilities (and linkages), in the hope of initiating a discussion and prompting action on climate change adaptation measures.